Villarreal have been a thorn in Real Madrid's flesh in recent years, holding them to several draws. The hosts are also riding a five-game winning streak.

This is the Reds' only shot at glory this season, so they will take it seriously. New signing Cody Gakpo, a World Cup star from the Netherlands, is expected to make his debut. The 23-year-old had three goals in Qatar and scored nine in 14 matches with PSV Eindhoven this season. He will join an attack that features Mohamed Salah (seven EPL goals) and Darwin Nunez (five). Liverpool have scored 34 goals in 17 league matches, while Wolves have scored just 11. Liverpool have won seven straight meetings with Wolves.

Liverpool have had some trouble on the back line but should be able to handle Wolverhampton. Caoimhin Kelleher is expected to get the nod in goal in place of Alisson, and the Irishman was a key part of the team's cup success last season. He saved three penalties in a shootout victory against Derby County in this year's EFL Cup before the Reds were ousted by Manchester City. Liverpool won the most recent matchup 3-1 at the end of last season. They held the ball for 63% of the match and outshot Wolves 29-7. Liverpool Wins.

QPR and Luton are both entering new periods under different managers but the R’s begin their new chapter in better shape than the Hatters and can be trusted to take all three points.

A lack of goals has been an issue for QPR since the uncertainty over Beale’s future emerged but the return of Ilias Chair and newfound stability in the dugout could prove a turning point.

The Londoners are not without a goal threat, scoring two or more goals in nine of their first 16 Championship outings of 2022-23. They should now be expected to address their recent slide and get back towards that level, so over 2.5 goals.

But the best bet looks a straight backing of QPR.